IRX3 variant as a modifier of Brugada syndrome with frequent ventricular fibrillation

Yoshitaka Kimura, MD, Takeshi Aiba, MD, PhD, Tetsuo Sasano, MD, PhD, Tetsushi Furukawa, MD, PhD, Kengo Kusano, MD, PhD, Wataru Shimizu, MD, PhD From the Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan, Department of Advanced Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan, Department of Biofunctional Informatics, Tokyo Medical and Dental University, Tokyo, Japan, Department of Bio-Informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan, and Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.